翻訳と辞書 Words near each other ・ Tue Marshes Light ・ Tue Rechnung! Donnerwort, BWV 168 ・ Tue West ・ Tueba Menayane ・ Tuebrook ・ Tuebrook and Stoneycroft (ward) ・ Tueeulala Falls ・ Tuek Chhou District ・ Tuek Chour ・ Tuek Phos (town) ・ Tuek Phos District ・ Tuek Thla ・ Tuek Thla, Banteay Meanchey ・ Tuek Thla, Phnom Penh ・ Tuel Lane Lock ・ Tudor domain ・ Tudor Drăganu ・ Tudor Farm Bank ・ Tudor Fieldhouse ・ Tudor Ganea ・ Tudor Gates ・ Tudor Gheorghe ・ Tudor Gheorghe Țopa ・ Tudor Giurgiu ・ Tudor Grange Academy ・ Tudor Grange Academy, Redditch ・ Tudor Grange Academy, Solihull ・ Tudor Grange Academy, Worcester ・ Tudor Grange Park ・ Tudor Gunasekara Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Tudor domain ： ウィキペディア英語版 Tudor domain In molecular biology a tudor domain is a conserved protein structural motif originally identified as a region of 50 amino acids found in the Tudor protein encoded in Drosophila. The structurally characterized Tudor domain in human SMN (survival of motor neuron) is a strongly bent anti-parallel β-sheet consisting of five β-strands with a barrel-like fold and recognizes symmetrically dimethylated arginine. The proteins TP53BP1 (Tumor suppressor p53-binding protein 1) and its fission yeast homolog Crb2 and JMJD2A (Jumonji domain containing 2A) contain either tandem or double Tudor domains and recognize methylated histones. Other tudor domain containing proteins include AKAP1 (A-kinase anchor protein 1) and ARID4A (AT rich interactive domain 4A) among others. A well known Tudor domain containing protein is Staphylococcal Nuclease Domain Containing 1 (SND1)/Tudor-SN/p100 co activator. SND1 is involved in RISC complex and interacts with AEG-1 oncogene. SND1 is also acts as an oncogene and plays very important role in HCC and colon cancer. The SND1 tudor domain binds to methylated arginine in the PIWIL1 protein.Tudor containing SND1 promotes tumor angiogenesis in human hepatocellular carcinoma through a novel pathway which involves NF-kappaB and miR-221. Tudor SND1 is also present in the ''Drosophila melanogaster''. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Tudor domain」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.